⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18773754 | 1.00 | — | — | |
| SCHEMBL7937981 | 0.80 | — | — | |
| SCHEMBL22879505 | 0.80 | — | — | |
| SCHEMBL1109085 | 0.80 | — | — | |
| SCHEMBL20825162 | 0.80 | — | — | |
| SCHEMBL13824102 | 0.80 | — | — | |
| SCHEMBL25829096 | 0.78 | — | — | |
| SCHEMBL21183081 | 0.77 | — | — | |
| SCHEMBL16508310 | 0.77 | — | — | |
| SCHEMBL23172859 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348460-A1 | ANTI-WOLBACHIA PYRIDO[2,3-d]PYRIMIDINECOMPOUNDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2023-11-02 | — | — | US | disclosed |
| WO-2023133260-A2 | CHEMICAL TARGETING SWI/SNF RELATED, MATRIX ASSOCIATED, ACTIN DEPENDENT REGULATOR OF CHROMATIN, SUBFAMILY A, MEMBER 4 (SMARCA4) AND USE IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-07-13 | — | — | WO | disclosed |
| WO-2022173743-A1 | COMPOUNDS AND METHODS FOR PREVENTING, TREATING, OR AMELIORATING AIRWAY DISEASE | THOMAS JEFFERSON UNIVERSITY (US) | 2022-08-18 | — | — | WO | disclosed |