Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 18/20 | 0.71 |
| ▸ | PPARA | Q07869 | 13/20 | 0.71 |
| ▸ | PPARG | P37231 | 8/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2463904 | 0.92 | PPARD (0.70) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5697537 | 0.92 | PPARD (0.71) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5697527 | 0.85 | PPARD (0.74) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5655360 | 0.85 | PPARD (0.71) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5697544 | 0.84 | PPARD (0.73) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL2466289 | 0.84 | PPARD (0.72) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL2167820 | 0.84 | PPARD (0.81) | PPARDPPARAPPARG | |
| SCHEMBL5656190 | 0.84 | PPARD (0.75) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL2463458 | 0.82 | PPARD (0.70) | PPARDPPARAPPARG | |
| SCHEMBL4725870 | 0.80 | PPARD (0.74) | PPARDPPARAPPARGFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1424330-B1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR DELTA | NIPPON CHEMIPHAR CO (JP) | 2011-09-28 | — | — | EP | disclosed |
| US-7652045-B2 | e.g. [[7-Allyl-3-[2-[2-(2,4-dichlorophenyl)-5-isopropyl-4-oxazolyl]ethyl]-1,2-benzisoxazol-6-yl]oxy]acetic acid; with vehicles (lactose, D-mannitol, glucose), disintegrators (starch or carboxymethylcellulose calcium ), binders (hydroxypropylcellulose) and lubricants (magnesium stearate or talc) | NIPPON CHEMIPHAR, CO., LTD. (JP) | 2010-01-26 | — | — | US | disclosed |
| US-7648999-B2 | Activator for peroxisome proliferator-activated receptor δ | NIPPON CHEMIPHAR CO., LTD. (JP) | 2010-01-19 | — | — | US | disclosed |
| US-20080009525-A1 | Activator of peroxisome proliferator-activated receptor delta | SAKUMA SHOGO | 2008-01-10 | — | — | US | disclosed |
| US-20080009631-A1 | Activator for peroxisome proliferator-activated receptor delta | SAKUMA SHOGO | 2008-01-10 | — | — | US | disclosed |
| US-7265137-B2 | Activator of peroxisome proliferator-activated re-ceptor δ | NIPPON CHEMIPHAR CO., LTD. (JP) | 2007-09-04 | — | — | US | disclosed |
| EP-1343772-B1 | THIA- AND OXAZOLES AND THEIR USE AS PPARS ACTIVATORS | GLAXO GROUP LTD (GB) | 2006-05-31 | — | — | EP | disclosed |
| US-20050054674-A1 | Activator of peroxisome proliferator-activated receptor | NIPPON CHEMIPHAR CO., LTD. (JP) | 2005-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009525-A1 | Activator of peroxisome proliferator-activated receptor delta | PPARG, PPARD, PPARA | PPARD 2/4885PPARA 3/4885PPARG 1/4885 |
| US-20080009631-A1 | Activator for peroxisome proliferator-activated receptor delta | PPARG, PPARD, PPARA | PPARD 2/4885PPARA 3/4885PPARG 1/4885 |
| US-20050054674-A1 | Activator of peroxisome proliferator-activated receptor | PPARG, PPARD, PPARA | PPARD 2/4885PPARA 3/4885PPARG 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.