Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115135 | 0.89 | CA12 (0.47) | CA12CA1CA9CYP17A1BRD4 | |
| SCHEMBL2997209 | 0.84 | EPHX2 (0.46) | CA12CA1CA9CYP17A1BRD4 | |
| SCHEMBL14464304 | 0.81 | CA12 (0.43) | CA12CA1CA9CYP17A1BRD4 | |
| SCHEMBL1115122 | 0.78 | CA12 (0.47) | CA12CA1CA9CYP17A1BRD4 | |
| SCHEMBL2465279 | 0.77 | CA12 (0.46) | CA12CA1CA9CYP17A1BRD4 | |
| SCHEMBL14872697 | 0.77 | CA12 (0.38) | CA12CA1CA9CYP17A1BRD4 | |
| SCHEMBL22664849 | 0.76 | CA12 (0.45) | CA12CA1CA9BRD4CREBBP | |
| SCHEMBL17472011 | 0.76 | CA12 (0.37) | CA12CA1CA9CYP17A1BRD4 | |
| SCHEMBL25318971 | 0.75 | CA12 (0.47) | CA12CA1CA9CYP17A1BRD4 | |
| SCHEMBL31555353 | 0.75 | CA12 (0.47) | CA12CA1CA9CYP17A1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364735-A2 | Branched PEG conjugates of GLP-1 | Nektar Therapeutics (US) | 2011-09-14 | — | — | EP | disclosed |