Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 20/20 | 0.68 |
| ▸ | JAK1 | P23458 | 20/20 | 0.68 |
| ▸ | TYK2 | P29597 | 20/20 | 0.68 |
| ▸ | JAK3 | P52333 | 11/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24653286 | 1.00 | JAK2 (0.68) | JAK2JAK1TYK2JAK3CYP2C19 | |
| SCHEMBL23424244 | 0.93 | JAK2 (0.73) | JAK2JAK1TYK2JAK3CYP2C19 | |
| SCHEMBL21757106 | 0.86 | JAK2 (0.90) | JAK2JAK1TYK2JAK3CYP2C19 | |
| SCHEMBL21757020 | 0.86 | JAK2 (0.90) | JAK2JAK1TYK2JAK3CYP2C19 | |
| SCHEMBL23584394 | 0.86 | JAK2 (0.90) | JAK2JAK1TYK2JAK3CYP2C19 | |
| SCHEMBL21757002 | 0.86 | JAK2 (0.90) | JAK2JAK1TYK2JAK3CYP2C19 | |
| SCHEMBL21757170 | 0.85 | JAK2 (0.83) | JAK2JAK1TYK2JAK3CYP2C19 | |
| SCHEMBL21757015 | 0.85 | JAK2 (0.83) | JAK2JAK1TYK2JAK3CYP2C19 | |
| SCHEMBL21757058 | 0.85 | JAK2 (0.83) | JAK2JAK1TYK2JAK3CYP2C19 | |
| SCHEMBL23424241 | 0.84 | JAK2 (0.69) | JAK2JAK1TYK2JAK3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022161205-A1 | ORAL PREPARATION CONTAINING JAK INHIBITOR OR SALT THEREOF OR CRYSTAL FORM THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 珠海联邦制药股份有限公司 | 2022-08-04 | — | — | WO | disclosed |