Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 14/20 | 0.54 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.49 |
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2471372 | 0.93 | SCD (0.54) | SCDDCTPP1GBA1 | |
| SCHEMBL2466129 | 0.92 | SCD (0.54) | SCDDCTPP1 | |
| SCHEMBL2467138 | 0.92 | SCD (0.54) | SCDDCTPP1GBA1 | |
| SCHEMBL2464871 | 0.92 | SCD (0.60) | SCDDCTPP1 | |
| SCHEMBL2466920 | 0.91 | SCD (0.55) | SCDDCTPP1 | |
| SCHEMBL2471742 | 0.91 | SCD (0.54) | SCDDCTPP1GBA1 | |
| SCHEMBL2466843 | 0.91 | SCD (0.58) | SCDDCTPP1 | |
| SCHEMBL2464753 | 0.89 | SCD (0.55) | SCDDCTPP1 | |
| SCHEMBL2469836 | 0.88 | SCD (0.54) | SCDDCTPP1 | |
| SCHEMBL2468464 | 0.88 | SCD (0.57) | SCDDCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648874-B1 | PIPERAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2011-10-05 | — | — | EP | claimed |
| EP-1846035-B1 | COMBINATION THERAPY | XENON PHARMACEUTICALS INC (CA) | 2011-09-21 | — | — | EP | claimed |