Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 16/20 | 0.46 |
| ▸ | FGR | P09769 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | TEC | P42680 | 1/20 | 0.35 |
| ▸ | BMX | P51813 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2464208 | 1.00 | BTK (0.46) | BTKFGRSRCTECBMX | |
| SCHEMBL2465023 | 1.00 | BTK (0.46) | BTKFGRSRCTECBMX | |
| SCHEMBL2459299 | 1.00 | BTK (0.46) | BTKFGRSRCTECBMX | |
| SCHEMBL2461624 | 1.00 | BTK (0.46) | BTKFGRSRCTECBMX | |
| SCHEMBL2462882 | 0.88 | BTK (0.45) | BTKFGRSRCTECBMX | |
| SCHEMBL2465092 | 0.88 | BTK (0.45) | BTKFGRSRCTECBMX | |
| SCHEMBL2464638 | 0.86 | BTK (0.46) | BTKFGRSRCTECBMX | |
| SCHEMBL2461867 | 0.86 | BTK (0.46) | BTKFGRSRCTECBMX | |
| SCHEMBL2463590 | 0.86 | BTK (0.46) | BTKFGRSRCTECBMX | |
| SCHEMBL9984873 | 0.84 | BTK (0.48) | BTKFGRSRCTECBMX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2365970-A1 | Pyridazinones and their use as btk inhibitors | CGI Pharmaceuticals, Inc. (US) | 2011-09-21 | — | — | EP | claimed |
| WO-2010056875-A1 | PYRIDAZINONES AND THEIR USE AS BTK INHIBITORS | CGI PHARMACEUTICALS, INC. (US) | 2010-05-20 | — | — | WO | claimed |
| EP-2365970-A1 | Pyridazinones and their use as btk inhibitors | CGI Pharmaceuticals, Inc. (US) | 2011-09-21 | — | — | EP | disclosed |
| WO-2010056875-A1 | PYRIDAZINONES AND THEIR USE AS BTK INHIBITORS | CGI PHARMACEUTICALS, INC. (US) | 2010-05-20 | — | — | WO | disclosed |