Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 15/20 | 0.63 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2469792 | 0.89 | SCD (0.63) | SCDDCTPP1 | |
| SCHEMBL2470069 | 0.88 | SCD (0.69) | SCDDCTPP1 | |
| SCHEMBL2466218 | 0.88 | SCD (0.70) | SCDDCTPP1 | |
| SCHEMBL2469589 | 0.87 | SCD (0.72) | SCDDCTPP1 | |
| SCHEMBL2468393 | 0.87 | SCD (0.74) | SCDDCTPP1 | |
| SCHEMBL2464830 | 0.87 | SCD (0.69) | SCDDCTPP1 | |
| SCHEMBL2468894 | 0.87 | SCD (0.57) | SCDDCTPP1 | |
| SCHEMBL2470120 | 0.86 | SCD (0.54) | SCDDCTPP1 | |
| SCHEMBL2468444 | 0.86 | SCD (0.74) | SCDDCTPP1 | |
| SCHEMBL2469801 | 0.86 | SCD (0.74) | SCDDCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846035-B1 | COMBINATION THERAPY | XENON PHARMACEUTICALS INC (CA) | 2011-09-21 | — | — | EP | claimed |