Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 20/20 | 0.78 |
| ▸ | LYN | P07948 | 18/20 | 0.78 |
| ▸ | KDR | P35968 | 18/20 | 0.78 |
| ▸ | SRC | P12931 | 16/20 | 0.78 |
| ▸ | INSR | P06213 | 14/20 | 0.78 |
| ▸ | HCK | P08631 | 12/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2471113 | 0.87 | LCK (1.00) | LCKLYNKDRSRCINSR | |
| SCHEMBL2466467 | 0.85 | LCK (0.79) | LCKLYNKDRSRCINSR | |
| SCHEMBL2466932 | 0.80 | LCK (0.53) | LCKLYNKDRSRCINSR | |
| SCHEMBL2468747 | 0.79 | LCK (0.71) | LCKLYNKDRSRCINSR | |
| SCHEMBL2465773 | 0.79 | LCK (1.00) | LCKLYNKDRSRCINSR | |
| SCHEMBL2465736 | 0.77 | LCK (1.00) | LCKLYNKDRSRCINSR | |
| SCHEMBL2466908 | 0.77 | LCK (1.00) | LCKLYNKDRSRCINSR | |
| SCHEMBL2465102 | 0.76 | LCK (0.74) | LCKLYNKDRSRCINSR | |
| SCHEMBL2465425 | 0.76 | LCK (0.80) | LCKLYNKDRSRCINSR | |
| SCHEMBL2465599 | 0.76 | LCK (1.00) | LCKLYNKDRSRCINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899329-B1 | PYRIMIDINE-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2011-10-05 | — | — | EP | claimed |