Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 16/20 | 0.56 |
| ▸ | PPARA | Q07869 | 15/20 | 0.56 |
| ▸ | PPARG | P37231 | 10/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24742435 | 0.93 | PPARD (0.54) | PPARDPPARAPPARGMAPTFFAR1 | |
| SCHEMBL1765848 | 0.93 | PPARA (0.66) | PPARDPPARAPPARG | |
| SCHEMBL12732444 | 0.93 | PPARD (0.57) | PPARDPPARAPPARGMAPTFFAR1 | |
| SCHEMBL2464886 | 0.90 | PPARD (0.55) | PPARDPPARAPPARGMAPTKDM4E | |
| SCHEMBL24742378 | 0.89 | PPARD (0.49) | PPARDPPARAPPARGMAPTKDM4E | |
| SCHEMBL2462565 | 0.88 | PPARD (0.56) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL12732450 | 0.88 | PPARD (0.49) | PPARDPPARAPPARGMAPTFFAR1 | |
| SCHEMBL2464420 | 0.86 | PPARD (0.60) | PPARDPPARAPPARGMAPTFFAR1 | |
| SCHEMBL2466100 | 0.86 | PPARD (0.54) | PPARDPPARAPPARGMAPTKDM4E | |
| SCHEMBL24742581 | 0.86 | PPARD (0.54) | PPARDPPARAPPARGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022189856-A9 | COMPOUNDS USEFUL FOR TREATING LIVER DISEASES | ABIONYX PHARMA SA (FR) | 2022-10-13 | — | — | WO | disclosed |