Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24658387 | 0.82 | MAPT (0.53) | MAPTATMTSHRNPSR1L3MBTL1 | |
| SCHEMBL24658418 | 0.79 | MAPT (0.50) | MAPTATMTSHRNPSR1L3MBTL1 | |
| SCHEMBL24659076 | 0.79 | MAPT (0.53) | MAPTATMTSHRNPSR1L3MBTL1 | |
| SCHEMBL22477387 | 0.78 | HRH3 (0.45) | TSHRNPSR1L3MBTL1HTTMEN1 | |
| SCHEMBL2603226 | 0.77 | MAPT (0.55) | MAPTATMTSHRNPSR1HTT | |
| SCHEMBL23706754 | 0.77 | MAPT (0.55) | MAPTATMTSHRNPSR1HTT | |
| SCHEMBL13014522 | 0.76 | MAPT (0.59) | MAPTATMTSHRNPSR1MEN1 | |
| SCHEMBL23155886 | 0.76 | MAPT (0.59) | MAPTATMTSHRNPSR1MEN1 | |
| SCHEMBL12464288 | 0.74 | SLC18A3 (0.41) | HTTKMT2ASLC18A3LMNAALDH1A1 | |
| SCHEMBL23706772 | 0.74 | MAPT (0.52) | MAPTATMTSHRNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022173756-A1 | ANTIBACTERIAL COMPOUNDS | FORGE THERAPEUTICS, INC. (US) | 2022-08-18 | — | — | WO | disclosed |