SCHEMBL24660941

SCHEMBL24660941

CC1CC(c2cccc(-n3cc4c(C(F)(F)F)cc(CN5CCC[C@H](C)C5)cn4c3=O)c2)(c2nncn2C)C1

nearest known ligand 0.77

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.77
▸ CBL P22681 7/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24660931 1.00 CBLB (0.77) CBLBCBL
SCHEMBL24661677 1.00 CBLB (0.77) CBLBCBL
SCHEMBL26785595 0.95 CBLB (0.71) CBLBCBL
SCHEMBL26785598 0.95 CBLB (0.71) CBLBCBL
SCHEMBL24660843 0.95 CBLB (0.70) CBLBCBL
SCHEMBL24662846 0.95 CBLB (0.69) CBLBCBL
SCHEMBL24661561 0.95 CBLB (0.69) CBLBCBL
SCHEMBL26665073 0.94 CBLB (0.69) CBLBCBL
SCHEMBL24662312 0.93 CBLB (0.68) CBLBCBL
SCHEMBL26665081 0.93 CBLB (0.68) CBLBCBL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4653436-A1 HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF GUANGZHOU YUFAN NANTU BIOTECHNOLOGIES CO., LTD (CN) 2025-11-26 — — EP disclosed
WO-2024153240-A1 HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF 珠海宇繁生物科技有限责任公司 2024-07-25 — — WO disclosed
US-20230355599-A1 BIOMARKERS FOR CBL, AND COMPOSITIONS AND METHODS FOR THEIR USE NURIX THERAPEUTICS, INC. 2023-11-09 — — US disclosed
WO-2022221704-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING CANCER HOTSPOT THERAPEUTICS, INC. (US) 2022-10-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230355599-A1 BIOMARKERS FOR CBL, AND COMPOSITIONS AND METHODS FOR THEIR USE CBL, CBLB, CBLC CBLB 2/4885CBL 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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