Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 20/20 | 0.50 |
| ▸ | CBL | P22681 | 1/20 | 0.43 |
| ▸ | CBLC | Q9ULV8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24661550 | 0.93 | CBLB (0.53) | CBLBCBLCBLC | |
| SCHEMBL24661551 | 0.92 | CBLB (0.50) | CBLBCBLCBLC | |
| SCHEMBL24661460 | 0.92 | CBLB (0.51) | CBLBCBLCBLC | |
| SCHEMBL24661461 | 0.91 | CBLB (0.51) | CBLBCBLCBLC | |
| SCHEMBL24661478 | 0.91 | CBLB (0.53) | CBLBCBL | |
| SCHEMBL24661466 | 0.90 | CBLB (0.56) | CBLBCBLCBLC | |
| SCHEMBL24660855 | 0.87 | CBLB (0.67) | CBLBCBL | |
| SCHEMBL24661431 | 0.87 | CBLB (0.54) | CBLBCBLCBLC | |
| SCHEMBL24661132 | 0.87 | CBLB (0.54) | CBLBCBLCBLC | |
| SCHEMBL24662549 | 0.87 | CBLB (0.58) | CBLBCBL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022221704-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING CANCER | HOTSPOT THERAPEUTICS, INC. (US) | 2022-10-20 | — | — | WO | disclosed |