Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 9/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
| ▸ | CBL | P22681 | 5/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31578412 | 0.87 | CBLB (0.63) | CBLBHCRTR1HCRTR2CBL | |
| SCHEMBL31115401 | 0.87 | CBLB (0.63) | CBLBHCRTR1HCRTR2CBL | |
| SCHEMBL27273961 | 0.82 | CBLB (0.53) | CBLBHCRTR1HCRTR2 | |
| SCHEMBL29866714 | 0.77 | HCRTR1 (0.44) | CBLBHCRTR1HCRTR2BRD4CYP17A1 | |
| SCHEMBL22528071 | 0.75 | CBLB (0.43) | CBLBHCRTR1HCRTR2BRD4CYP17A1 | |
| SCHEMBL29536246 | 0.75 | CBLB (0.66) | CBLBHCRTR1HCRTR2CBL | |
| SCHEMBL24662527 | 0.74 | CBLB (0.63) | CBLBHCRTR1HCRTR2 | |
| SCHEMBL24661075 | 0.74 | CBLB (0.44) | CBLBCBL | |
| SCHEMBL27273942 | 0.73 | HCRTR1 (0.50) | HCRTR1HCRTR2BRD4CYP17A1CYP3A4 | |
| SCHEMBL24662646 | 0.73 | CBLB (0.41) | CBLBCBL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022221704-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING CANCER | HOTSPOT THERAPEUTICS, INC. (US) | 2022-10-20 | — | — | WO | disclosed |