Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15533188 | 0.86 | CYP2C9 (0.50) | CYP2C9TSHRCYP2C19TDP1 | |
| SCHEMBL9820867 | 0.86 | CYP2C9 (0.33) | CYP2C9TSHRCYP2C19TDP1 | |
| SCHEMBL8665389 | 0.85 | PLG (0.31) | — | |
| SCHEMBL6380793 | 0.75 | TSHR (0.33) | CYP2C9TSHRCYP2C19TDP1 | |
| SCHEMBL22598596 | 0.74 | — | — | |
| SCHEMBL21942645 | 0.73 | — | — | |
| SCHEMBL4602653 | 0.72 | — | — | |
| SCHEMBL11607063 | 0.72 | — | — | |
| SCHEMBL24350290 | 0.72 | — | — | |
| SCHEMBL15828874 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023172737-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-09-14 | — | — | WO | disclosed |
| WO-2022266015-A1 | FUSED HETEROARYL COMPOUNDS USEFUL AS ANTICANCER AGENTS | KUMQUAT BIOSCIENCES INC. (US) | 2022-12-22 | — | — | WO | disclosed |
| WO-2022214102-A1 | HETEROCYCLIC COMPOUND ACTING AS KRAS G12D INHIBITOR | 杭州英创医药科技有限公司 | 2022-10-13 | — | — | WO | disclosed |