Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 20/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 20/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 20/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4014079 | 0.99 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1918433 | 0.90 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30074724 | 0.90 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2466398 | 0.87 | PDE4B (0.48) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2466399 | 0.86 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6155742 | 0.86 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6155940 | 0.86 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7381565 | 0.84 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6154541 | 0.83 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7380391 | 0.83 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803760-B2 | Methods of inducing ovulation | MERCK SERONO SA (CH) | 2010-09-28 | — | — | US | claimed |
| US-20080293622-A1 | METHODS OF INDUCING OVULATION | MERCK SERONO SA (CH) | 2008-11-27 | — | — | US | claimed |
| US-6953774-B2 | Methods of inducing ovulation | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2005-10-11 | — | — | US | claimed |
| US-20050148501-A1 | Methods of inducing ovulation using a non-polypeptide camp level modulator | MERCK SERONO SA (CH) | 2005-07-07 | — | — | US | claimed |
| US-20020103106-A1 | Methods of inducing ovulation | MERCK SERONO SA (CH) | 2002-08-01 | — | — | US | claimed |
| EP-1908463-B1 | Methods of inducing ovulation using a non-polypeptide camp level modulator | MERCK SERONO SA (CH) | 2011-09-28 | — | — | EP | disclosed |
| US-7507707-B2 | Methods of inducing ovulation using a non-polypeptide camp level modulator | LABORATOIRES SERONO SA (CH) | 2009-03-24 | — | — | US | disclosed |
| US-7364910-B2 | Methods of inducing ovulation | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2008-04-29 | — | — | US | disclosed |
| EP-1908463-A2 | Methods of inducing ovulation using a non-polypeptide camp level modulator | Laboratoires Serono SA (CH) | 2008-04-09 | — | — | EP | disclosed |
| US-20060293222-A1 | METHODS OF INDUCING OVULATION | MERCK SERONO SA (CH) | 2006-12-28 | — | — | US | disclosed |
| US-7078236-B2 | Methods of inducing ovulation | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2006-07-18 | — | — | US | disclosed |
| US-20060003925-A1 | Methods of inducing ovulation | MERCK SERONO SA (CH) | 2006-01-05 | — | — | US | disclosed |
| US-6953774-B2 | Methods of inducing ovulation | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2005-10-11 | — | — | US | disclosed |
| US-20050148501-A1 | Methods of inducing ovulation using a non-polypeptide camp level modulator | MERCK SERONO SA (CH) | 2005-07-07 | — | — | US | disclosed |
| EP-1463493-A1 | METHODS OF INDUCING OVULATION-USING A NON-POLYPEPTIDE CAMP LEVEL MODULATOR | Applied Research Systems ARS Holding N.V. (AN) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003051344-A1 | METHODS OF INDUCING OVULATION_USING A NON-POLYPEPTIDE CAMP LEVEL MODULATOR | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-06-26 | — | — | WO | disclosed |
| US-20020103106-A1 | Methods of inducing ovulation | MERCK SERONO SA (CH) | 2002-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293222-A1 | METHODS OF INDUCING OVULATION | PDE4A, PDE4B, PDE4C | PDE4A 1/4885PDE4B 2/4885PDE4C 3/4885 |
| US-20050148501-A1 | Methods of inducing ovulation using a non-polypeptide camp level modulator | PDE4A, PDE4B, PDE4C | PDE4A 1/4885PDE4B 2/4885PDE4C 3/4885 |
| US-20060003925-A1 | Methods of inducing ovulation | PDE4A, PDE4B, PDE4C | PDE4A 1/4885PDE4B 2/4885PDE4C 3/4885 |
| US-20020103106-A1 | Methods of inducing ovulation | PDE4A, PDE4B, PDE4C | PDE4A 1/4885PDE4B 2/4885PDE4C 3/4885 |
| US-20080293622-A1 | METHODS OF INDUCING OVULATION | PDE4A, PDE4B, PDE4C | PDE4A 1/4885PDE4B 2/4885PDE4C 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.