⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2153288 | 0.67 | TSHR (1.00) | — | |
| SCHEMBL1936538 | 0.67 | — | — | |
| SCHEMBL22537 | 0.67 | — | — | |
| SCHEMBL585572 | 0.65 | — | — | |
| SCHEMBL156986 | 0.64 | TSHR (0.43) | — | |
| SCHEMBL7873106 | 0.64 | — | — | |
| SCHEMBL277066 | 0.64 | TSHR (0.43) | — | |
| SCHEMBL18131684 | 0.64 | — | — | |
| SCHEMBL134136 | 0.63 | — | — | |
| SCHEMBL597698 | 0.63 | TSHR (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292790-A | Modified butadiene-styrene copolymer and carbon black; high strength, abrasion resistance, low fuel consumption after vulcanization | BRIDGESTONE CORPORATION (JP) | 1994-03-08 | — | — | US | claimed |
| US-5021380-A | Contacting nickel/II/ compound with organophosphine and bidentate nitrogen-containing ligands and tertiary-alkyl organometallic compound in nonpolar ether solvent to form nickel/0/ species | EASTMAN KODAK COMPANY (US) | 1991-06-04 | — | — | US | claimed |
| US-4939309-A | REACTING ARYL HALIDE WITH NICKEL-ORGANOPHOSPHINE-ORGANOMETAL-LIC-BIDENTATE LIGAND CATALYST | EASTMAN KODAK COMPANY (US) | 1990-07-03 | — | — | US | claimed |
| EP-1980575-B1 | A METHOD OF GEL INHIBITION FOR THE HOMOPOLYMERIZATION OR COPOLYMERIZATION PROCESS OF CONJUGATED DIENE | CHINA PETROLEUM & CHEMICAL (CN) | 2011-09-07 | — | — | EP | disclosed |
| EP-1980575-A1 | A METHOD OF GEL INHIBITION FOR THE HOMOPOLYMERIZATION OR COPOLYMERIZATION PROCESS OF CONJUGATED DIENE | China Petroleum & Chemical Corporation (CN) | 2008-10-15 | — | — | EP | disclosed |
| US-6784305-B2 | DERIVATIVES OF ZIRCONOCENE DICHLORIDE IN WHICH THE TWO SUBSTITUTED INDENYL GROUPS ARE JOINED TO ONE ANOTHER VIA A BRIDGE CAN, OWING TO THEIR CONFORMATIONAL RIGIDITY, BE USED AS CATALYSTS FOR THE STEREOSPECIFIC POLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2004-08-31 | — | — | US | disclosed |
| US-20030236439-A1 | Non-steroidal analogs of 2-methoxyestradiol | ENTREMED, INC. | 2003-12-25 | — | — | US | disclosed |
| US-20030199703-A1 | Method for producing alkyl-bridged ligand systems and transition metal compounds | EQUISTAR CHEMICALS, LP | 2003-10-23 | — | — | US | disclosed |
| US-20030187076-A1 | Non-steroidal analogs of 2-methoxyestradiol | ENTREMED, INC. | 2003-10-02 | — | — | US | disclosed |
| WO-2003063791-A2 | NON-STEROIDAL ANALOGS OF 2-METHOXYESTRADIOL | ENTREMED, INC. (US) | 2003-08-07 | — | — | WO | disclosed |
| WO-2003063787-A2 | NON-STEROIDAL ANALOGS OF 2-METHOXYESTRADIOL | ENTREMED, INC. (US) | 2003-08-07 | — | — | WO | disclosed |
| EP-0593049-A1 | Anionic polymerization initiators and reduced hysteresis products therefrom | BRIDGESTONE CORPORATION (JP) | 1994-04-20 | — | — | EP | disclosed |
| US-5292790-A | Modified butadiene-styrene copolymer and carbon black; high strength, abrasion resistance, low fuel consumption after vulcanization | BRIDGESTONE CORPORATION (JP) | 1994-03-08 | — | — | US | disclosed |
| US-5021380-A | Contacting nickel/II/ compound with organophosphine and bidentate nitrogen-containing ligands and tertiary-alkyl organometallic compound in nonpolar ether solvent to form nickel/0/ species | EASTMAN KODAK COMPANY (US) | 1991-06-04 | — | — | US | disclosed |
| US-4939309-A | REACTING ARYL HALIDE WITH NICKEL-ORGANOPHOSPHINE-ORGANOMETAL-LIC-BIDENTATE LIGAND CATALYST | EASTMAN KODAK COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| US-4525560-A | PRODUCING HIGH LEVELS OF POLYMER SOLIDS WITHOUT REQUIRING COOLING,INCREMENTAL ADDITIONS, RECYCLING A PORTION OF TERMINATED POLYMER | SMITH RICHARD L | 1985-06-25 | — | — | US | disclosed |
| US-4311803-A | Continuous solution polymerization process | PHILLIPS PETROLEUM COMPANY (US) | 1982-01-19 | — | — | US | disclosed |
| EP-0019100-A1 | Continuous solution polymerization process | PHILLIPS PETROLEUM COMPANY (US) | 1980-11-26 | — | — | EP | disclosed |
| US-4137391-A | Continuous solution polymerization of a conjugated diene with a monovinylaromatic compound using alkoxysilicon treating agents in the first reactor means of a reactor series | PHILLIPS PETROLEUM COMPANY (US) | 1979-01-30 | — | — | US | disclosed |
| US-4091198-A | Suppressing gel in the continuous solution polymerization of a conjugated diene with a monovinyl aromatic compound | PHILLIPS PETROLEUM COMPANY (US) | 1978-05-23 | — | — | US | disclosed |