Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.33 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.33 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.33 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.30 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24791785 | 0.89 | TMPRSS2 (0.79) | TMPRSS2LGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL24667695 | 0.89 | TMPRSS2 (0.52) | TMPRSS2EGLN2 | |
| SCHEMBL24917569 | 0.84 | TMPRSS2 (0.63) | TMPRSS2POLBEGLN2NPC1ALDH1A1 | |
| SCHEMBL26136380 | 0.84 | TMPRSS2 (0.63) | TMPRSS2POLBEGLN2NPC1ALDH1A1 | |
| SCHEMBL24791240 | 0.83 | TMPRSS2 (0.61) | TMPRSS2POLBEGLN2NPC1ALDH1A1 | |
| SCHEMBL24667620 | 0.83 | TMPRSS2 (0.53) | TMPRSS2POLBEGLN2NPC1ALDH1A1 | |
| SCHEMBL24917209 | 0.82 | TMPRSS2 (0.60) | TMPRSS2POLBEGLN2NPC1ALDH1A1 | |
| SCHEMBL24789441 | 0.82 | TMPRSS2 (0.60) | TMPRSS2POLBEGLN2NPC1ALDH1A1 | |
| SCHEMBL26136509 | 0.82 | TMPRSS2 (0.60) | TMPRSS2POLBEGLN2NPC1ALDH1A1 | |
| SCHEMBL25315489 | 0.82 | TMPRSS2 (0.62) | TMPRSS2EGLN2NPC1ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022219636-A1 | ANTI-VIRAL AND ANTI-TUMORAL COMPOUNDS, AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2022-10-20 | — | — | WO | disclosed |