SCHEMBL246679

SCHEMBL246679

[CH2]C(C)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4673312 1.00
SCHEMBL4678295 1.00
SCHEMBL5390688 0.78
SCHEMBL8356458 0.75
SCHEMBL8355038 0.75
SCHEMBL21295947 0.72
SCHEMBL19950766 0.70
SCHEMBL15638641 0.70
SCHEMBL23164 0.70
SCHEMBL21561425 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 471 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024104932-A1 ARYL THIOETHERS AS HIF-2ALPHA INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2024-05-23 WO claimed
CN-116987083-A Pyrazolo [1,5-a ] pyrimidine derivative, preparation method and application thereof 杭州健崃生物科技有限公司 2023-11-03 CN claimed
US-RE49699-E1 Inhibitors of TRPC6 BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2023-10-17 US claimed
CN-115974713-A Fluorine-containing compound, preparation method and compound containing fluorine-containing compound 中国科学技术大学 2023-04-18 CN claimed
EP-3700902-B1 INHIBITORS OF TRPC6 BOEHRINGER INGELHEIM INT (DE) 2023-03-08 EP claimed
US-20220411421-A1 4-AMINO-IMIDAZOQUINOLINE COMPOUNDS AND USE THEREOF CHOU, YU-CHENG (TW) 2022-12-29 US claimed
CN-114599360-A 4-amino-imidazoquinoline compounds and uses thereof 骏达贸易有限公司 2022-06-07 CN claimed
WO-2021086689-A1 4-AMINO-IMIDAZOQUINOLINE COMPOUNDS AND USE THEREOF PRIME REACH TRADING LIMITED (WS) 2021-05-06 WO claimed
US-20200347071-A1 AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2020-11-05 US claimed
US-10800757-B2 Inhibitors of TRPC6 BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2020-10-13 US claimed
CN-1085223-A The 17-beta substitution-4-azepine-5 α-androstane-3-one derivative ERBA CARLO SPA (IT) 1994-04-13 CN claimed
WO-1994003475-A1 FLUORINATED 17β-SUBSTITUTED 4-AZA-5α-ANDROSTAN-3-ONE DERIVATIVES FARMITALIA CARLO ERBA S.R.L. (IT) 1994-02-17 WO claimed
WO-1994003476-A1 17β-SUBSTITUTED 4-AZA-5α-ANDROSTAN-3-ONE DERIVATIVES FARMITALIA CARLO ERBA S.R.L. (IT) 1994-02-17 WO claimed
EP-0468396-A1 Process for depositing a copper-containing layer Kali-Chemie Aktiengesellschaft (DE) 1992-01-29 EP claimed
US-4867780-A PRE- AND POSTEMERGENCE HERBICIDES ICI AMERICAS, INC. (US) 1989-09-19 US claimed
US-4840969-A APPLYING AS INSECTICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1989-06-20 US claimed
EP-0304966-A2 Beta-ketonitriles SHIONOGI & CO., LTD. (JP) 1989-03-01 EP claimed
EP-0135491-B1 HERBICIDAL 2,6-BIS-FLUOROMETHYL-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID ESTERS MONSANTO COMPANY (US) 1989-01-25 EP claimed
EP-0243668-A2 N-substituted benzamides BAYER AG (DE) 1987-11-04 EP claimed
EP-0135491-A1 Herbicidal 2,6-bis-fluoromethyl-dihydropyridine-3,5-dicarboxylic acid esters MONSANTO COMPANY (US) 1985-03-27 EP claimed