Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 2/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 2/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | TGM1 | P22735 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670246 | 1.00 | NAMPT (0.47) | NAMPTSCN9AL3MBTL1WDR5USP30 | |
| SCHEMBL24670908 | 0.94 | NAMPT (0.46) | NAMPTSCN9AL3MBTL1WDR5USP30 | |
| SCHEMBL29803380 | 0.93 | NAMPT (0.45) | NAMPTSCN9AL3MBTL1WDR5PDK4 | |
| SCHEMBL24669491 | 0.93 | CHRM1 (0.51) | NAMPTSCN9AL3MBTL1WDR5NPY2R | |
| SCHEMBL29803696 | 0.93 | NAMPT (0.52) | NAMPTSCN9AWDR5PDK4GRM5 | |
| SCHEMBL24669339 | 0.93 | NAMPT (0.52) | NAMPTSCN9AWDR5PDK4GRM5 | |
| SCHEMBL24669461 | 0.93 | NAMPT (0.45) | NAMPTSCN9AL3MBTL1WDR5USP30 | |
| SCHEMBL24670946 | 0.88 | NAMPT (0.49) | NAMPTSCN9AWDR5PDK4GRM5 | |
| SCHEMBL24670852 | 0.88 | NAMPT (0.49) | NAMPTSCN9AWDR5PDK4GRM5 | |
| SCHEMBL29803278 | 0.88 | NAMPT (0.49) | NAMPTSCN9AWDR5PDK4GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |