Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | FPR3 | P25089 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | STAT3 | P40763 | 2/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803661 | 0.94 | NAMPT (0.58) | NAMPTHDAC1HDAC6MAPTTDP1 | |
| SCHEMBL24669207 | 0.94 | NAMPT (0.58) | NAMPTHDAC1HDAC6MAPTTDP1 | |
| SCHEMBL29803548 | 0.89 | NAMPT (0.53) | NAMPTMAPTMAOBTP53NR1H4 | |
| SCHEMBL24669863 | 0.89 | NAMPT (0.53) | NAMPTMAPTMAOBTP53NR1H4 | |
| SCHEMBL30182179 | 0.88 | NAMPT (0.56) | NAMPTHDAC1HDAC6MAPTTDP1 | |
| SCHEMBL30182282 | 0.88 | NAMPT (0.52) | NAMPTHDAC1HDAC6MAPTTDP1 | |
| SCHEMBL24891826 | 0.85 | NAMPT (0.58) | NAMPTHDAC1HDAC6MAPTTDP1 | |
| SCHEMBL23899245 | 0.85 | NAMPT (0.72) | NAMPTHDAC1HDAC6MAPTTDP1 | |
| SCHEMBL24670224 | 0.84 | NAMPT (0.65) | NAMPTHDAC1HDAC6MAPTTDP1 | |
| SCHEMBL24891860 | 0.84 | NAMPT (0.65) | NAMPTHDAC1HDAC6MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |