Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30182423 | 0.87 | MAPT (0.69) | NAMPTMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL29803251 | 0.87 | MAPT (0.69) | NAMPTMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL24669994 | 0.87 | NAMPT (0.54) | NAMPTMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL24670148 | 0.86 | SMN1; SMN2 (0.50) | NAMPTMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11960760 | 0.85 | KMT2A (0.71) | NAMPTMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL24669214 | 0.85 | NAMPT (0.52) | NAMPTMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL24670887 | 0.85 | NAMPT (0.52) | NAMPTMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL24892305 | 0.85 | NAMPT (0.61) | NAMPTPTPN2PTPN1PTPN6 | |
| SCHEMBL11889756 | 0.85 | MAPT (0.68) | NAMPTMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL24670304 | 0.85 | NAMPT (0.51) | NAMPTMAPTSMN1; SMN2TP53CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |