Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL8013608 | 0.95 | — | — | |
| Ethyl Chloride SCHEMBL297727 | 0.84 | — | — | |
| Ethyl Chloride SCHEMBL28348613 | 0.78 | — | — | |
| Benzene SCHEMBL11503640 | 0.78 | TP53 (0.38) | TP53TSHR | |
| Ethyl Chloride SCHEMBL27882796 | 0.78 | — | — | |
| Ethyl Chloride SCHEMBL20021 | 0.78 | — | — | |
| Ethyl Chloride SCHEMBL1331853 | 0.78 | — | — | |
| Ethyl Chloride SCHEMBL1331994 | 0.78 | — | — | |
| Ethyl Chloride SCHEMBL1331389 | 0.78 | — | — | |
| Ethyl Chloride SCHEMBL1127611 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2587920-A1 | ANTIMICROBIAL COMBINATIONS OF PYRION COMPOUNDS WITH POLYETHYLENEIMINES | Janssen Pharmaceutica, N.V. (BE) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012001028-A1 | ANTIMICROBIAL COMBINATIONS OF PYRION COMPOUNDS WITH POLYETHYLENEIMINES | JANSSEN PHARMACEUTICA NV (BE) | 2012-01-05 | — | — | WO | disclosed |