Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 10/20 | 0.71 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.71 |
| ▸ | CCNA1 | P78396 | 5/20 | 0.71 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.71 |
| ▸ | CDK1 | P06493 | 14/20 | 0.60 |
| ▸ | CDK5 | Q00535 | 8/20 | 0.60 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.60 |
| ▸ | CDK7 | P50613 | 4/20 | 0.60 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.60 |
| ▸ | CDK9 | P50750 | 3/20 | 0.60 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.60 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.60 |
| ▸ | CLK2 | P49760 | 2/20 | 0.60 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.60 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.60 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.60 |
| ▸ | CCNK | O75909 | 2/20 | 0.60 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.60 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670401 | 0.88 | CDK2 (0.64) | CDK2CCNA2CCNA1CACNA1BCDK1 | |
| SCHEMBL24670404 | 0.84 | CDK2 (0.68) | CDK2CCNA2CCNA1CACNA1BCDK1 | |
| SCHEMBL17628623 | 0.83 | CDK2 (1.00) | CDK2CCNA2CCNA1CACNA1BCDK1 | |
| SCHEMBL5517026 | 0.83 | CDK2 (1.00) | CDK2CCNA2CCNA1CACNA1BCDK1 | |
| SCHEMBL24668659 | 0.82 | CDK2 (0.65) | CDK2CCNA2CCNA1CACNA1BCDK1 | |
| SCHEMBL24668640 | 0.82 | CDK2 (0.64) | CDK2CCNA2CCNA1CACNA1BCDK1 | |
| SCHEMBL28232529 | 0.82 | CDK2 (0.89) | CDK2CCNA2CCNA1CACNA1BCDK1 | |
| SCHEMBL28232469 | 0.81 | CDK2 (0.85) | CDK2CCNA2CCNA1CACNA1BCDK1 | |
| SCHEMBL24669725 | 0.81 | CDK2 (0.68) | CDK2CCNA2CCNA1CACNA1BCDK1 | |
| SCHEMBL28232483 | 0.81 | CDK2 (0.84) | CDK2CCNA2CCNA1CACNA1BCDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187693-A1 | COVALENT CDK2-BINDING COMPOUNDS FOR THERAPEUTIC PURPOSES | UMBRA THERAPEUTICS INC. (US) | 2022-09-09 | — | — | WO | disclosed |