Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803748 | 0.95 | NAMPT (0.40) | CHRM1MAPTNAMPTTRPV1LMNA | |
| SCHEMBL29803193 | 0.95 | NAMPT (0.40) | CHRM1MAPTNAMPTTRPV1SCN9A | |
| SCHEMBL24670289 | 0.94 | CHRM1 (0.44) | CHRM1MAPTLMNAMEN1ALDH1A1 | |
| SCHEMBL24670287 | 0.94 | CHRM1 (0.44) | CHRM1MAPTLMNAMEN1ALDH1A1 | |
| SCHEMBL24670759 | 0.92 | NAMPT (0.38) | MAPTNAMPTTRPV1LMNAMEN1 | |
| SCHEMBL29803415 | 0.92 | NAMPT (0.38) | MAPTNAMPTTRPV1LMNAMEN1 | |
| SCHEMBL24670758 | 0.92 | NAMPT (0.38) | MAPTNAMPTTRPV1LMNAMEN1 | |
| SCHEMBL24669451 | 0.92 | NAMPT (0.46) | MAPTNAMPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL24669446 | 0.92 | NAMPT (0.46) | MAPTNAMPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL24669385 | 0.91 | NAMPT (0.41) | NAMPTSCN9ANPC1TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |