Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | HTR1D | P28221 | 3/20 | 0.40 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670760 | 0.94 | NAMPT (0.45) | MAPTNPC1RAB9ANOS3NOS1 | |
| SCHEMBL29803737 | 0.90 | KMT2A (0.45) | MAPTNPC1RAB9ACA12CA2 | |
| SCHEMBL24669341 | 0.87 | CCNT1 (0.45) | NPC1RAB9ANOS3NOS1NAMPT | |
| SCHEMBL24671371 | 0.87 | CCNT1 (0.45) | NPC1RAB9ANOS3NOS1NAMPT | |
| SCHEMBL24671471 | 0.86 | CSF1R (0.40) | NAMPT | |
| SCHEMBL24670037 | 0.83 | CCNT1 (0.42) | MAPTNPC1RAB9ANOS3NOS1 | |
| SCHEMBL29803714 | 0.83 | NAMPT (0.51) | NPC1RAB9ANAMPT | |
| Trifluoroacetic Acid SCHEMBL29803973 | 0.83 | TRPV1 (0.41) | NPC1RAB9ACA12CA2CA7 | |
| SCHEMBL24671360 | 0.83 | CCNT1 (0.47) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29803643 | 0.83 | NPC1 (0.47) | MAPTNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |