Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.75 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.75 |
| ▸ | XBP1 | P17861 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.55 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.55 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.52 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.52 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.52 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.52 |
| ▸ | ACP1 | P24666 | 1/20 | 0.49 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803311 | 1.00 | MAPT (0.75) | MAPTNPSR1XBP1MEN1KMT2A | |
| SCHEMBL29803393 | 0.96 | MAPT (0.72) | MAPTNPSR1XBP1MEN1KMT2A | |
| SCHEMBL24671304 | 0.96 | MAPT (0.72) | MAPTNPSR1XBP1MEN1KMT2A | |
| SCHEMBL24669338 | 0.87 | MAOB (0.70) | MAPTNPSR1XBP1MEN1KMT2A | |
| SCHEMBL29803408 | 0.87 | MAOB (0.70) | MAPTNPSR1XBP1MEN1KMT2A | |
| SCHEMBL14785061 | 0.86 | MAPT (1.00) | MAPTNPSR1XBP1MEN1KMT2A | |
| SCHEMBL850791 | 0.83 | MEN1 (1.00) | MAPTNPSR1XBP1MEN1KMT2A | |
| SCHEMBL24671323 | 0.82 | MAOB (0.65) | MAPTNPSR1XBP1NPC1RAB9A | |
| SCHEMBL24670922 | 0.81 | TP53 (0.63) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL24670881 | 0.80 | MAOB (0.53) | MAPTNPSR1XBP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |