Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | WDR5 | P61964 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803672 | 1.00 | NAMPT (0.35) | NAMPTSCN9APDK4CDK9MAPT | |
| SCHEMBL24670282 | 1.00 | NAMPT (0.35) | NAMPTSCN9APDK4CDK9MAPT | |
| SCHEMBL24670288 | 0.95 | NAMPT (0.37) | NAMPTSCN9APDK4CDK9MAPT | |
| SCHEMBL24670858 | 0.95 | NAMPT (0.37) | NAMPTSCN9APDK4CDK9MAPT | |
| SCHEMBL24670281 | 0.94 | NAMPT (0.33) | NAMPTSCN9APDK4CDK9MAPT | |
| SCHEMBL24670759 | 0.92 | NAMPT (0.38) | NAMPTSCN9APDK4CDK9MAPT | |
| SCHEMBL29803415 | 0.92 | NAMPT (0.38) | NAMPTSCN9APDK4CDK9MAPT | |
| SCHEMBL24670758 | 0.92 | NAMPT (0.38) | NAMPTSCN9APDK4CDK9MAPT | |
| SCHEMBL29803193 | 0.92 | NAMPT (0.40) | NAMPTSCN9APDK4CDK9MAPT | |
| SCHEMBL24669463 | 0.90 | NAMPT (0.38) | NAMPTSCN9APDK4MAPTWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |