Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803492 | 1.00 | MEN1 (0.47) | MEN1KMT2ANAMPTSCN9ACHRM1 | |
| SCHEMBL24670838 | 0.92 | NAMPT (0.49) | MEN1KMT2ANAMPTSCN9AMAPT | |
| SCHEMBL29803464 | 0.92 | NAMPT (0.49) | MEN1KMT2ANAMPTSCN9AMAPT | |
| SCHEMBL29803380 | 0.90 | NAMPT (0.45) | MEN1KMT2ANAMPTSCN9ACHRM1 | |
| SCHEMBL29803371 | 0.90 | NAMPT (0.52) | MEN1KMT2ANAMPTSCN9AMAPT | |
| SCHEMBL24671142 | 0.90 | NAMPT (0.52) | MEN1KMT2ANAMPTSCN9AMAPT | |
| SCHEMBL24669994 | 0.88 | NAMPT (0.54) | MEN1KMT2ANAMPTSCN9ACHRM1 | |
| SCHEMBL24669491 | 0.87 | CHRM1 (0.51) | MEN1KMT2ANAMPTSCN9ACHRM1 | |
| SCHEMBL24671550 | 0.85 | NAMPT (0.49) | MEN1KMT2ANAMPTSCN9AMAPT | |
| SCHEMBL24670716 | 0.85 | NAMPT (0.53) | MEN1KMT2ANAMPTSCN9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |