Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 9/20 | 0.40 |
| ▸ | QDPR | P09417 | 2/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.34 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | LIPC | P11150 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670639 | 0.91 | NAMPT (0.39) | NAMPTQDPRSOS1PRMT5WDR77 | |
| SCHEMBL24670115 | 0.88 | NAMPT (0.43) | NAMPTQDPRSOS1PRMT5WDR77 | |
| SCHEMBL24670659 | 0.88 | NAMPT (0.41) | NAMPTQDPRSOS1PRMT5WDR77 | |
| SCHEMBL24670672 | 0.88 | NAMPT (0.41) | NAMPTQDPRSOS1PRMT5WDR77 | |
| SCHEMBL29803536 | 0.86 | NAMPT (0.40) | NAMPTQDPRSOS1PRMT5WDR77 | |
| SCHEMBL24669354 | 0.86 | NAMPT (0.42) | NAMPTQDPRSOS1PRMT5WDR77 | |
| SCHEMBL24670584 | 0.85 | NAMPT (0.42) | NAMPTQDPRSOS1PRMT5WDR77 | |
| SCHEMBL24670022 | 0.84 | NAMPT (0.42) | NAMPTQDPRSOS1PRMT5WDR77 | |
| SCHEMBL24669928 | 0.84 | NAMPT (0.44) | NAMPTQDPRPRMT5WDR77CDK7 | |
| SCHEMBL29803575 | 0.83 | NAMPT (0.40) | NAMPTSOS1PRMT5WDR77CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |