Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803204 | 1.00 | TMPRSS2 (0.52) | TMPRSS2MAPTPOLBHTR1DSLC6A4 | |
| SCHEMBL24669468 | 0.96 | TMPRSS2 (0.52) | TMPRSS2MAPTPOLBHTR1DSLC6A4 | |
| SCHEMBL24670713 | 0.93 | TMPRSS2 (0.57) | TMPRSS2MAPTPOLBHTR1DSLC6A4 | |
| SCHEMBL29803740 | 0.93 | TMPRSS2 (0.57) | TMPRSS2MAPTPOLBHTR1DSLC6A4 | |
| SCHEMBL29803214 | 0.93 | TMPRSS2 (0.52) | TMPRSS2MAPTLMNATRPV1NAMPT | |
| SCHEMBL29803358 | 0.90 | TMPRSS2 (0.47) | TMPRSS2MAPTHTR1DSLC6A4NPC1 | |
| SCHEMBL29802833 | 0.90 | TMPRSS2 (0.46) | TMPRSS2MAPTPOLBLMNATRPV1 | |
| SCHEMBL24669447 | 0.89 | TMPRSS2 (0.48) | TMPRSS2MAPTLMNANAMPTNPC1 | |
| SCHEMBL24671240 | 0.89 | TMPRSS2 (0.46) | TMPRSS2TRPV1 | |
| SCHEMBL29802859 | 0.89 | TMPRSS2 (0.46) | TMPRSS2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |