Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 5/20 | 0.51 |
| ▸ | PIP5K1C | O60331 | 14/20 | 0.37 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29207957 | 0.99 | ITK (0.50) | ITKPIP5K1CPTK6 | |
| Hydrochloric Acid SCHEMBL30066322 | 0.99 | ITK (0.50) | ITKPIP5K1CPTK6 | |
| SCHEMBL29990522 | 0.88 | ITK (0.53) | ITKPIP5K1C | |
| SCHEMBL24670928 | 0.88 | ITK (0.53) | ITKPIP5K1C | |
| SCHEMBL30801294 | 0.86 | ITK (0.50) | ITKPIP5K1C | |
| SCHEMBL24671805 | 0.86 | ITK (0.50) | ITKPIP5K1C | |
| SCHEMBL30801239 | 0.86 | ITK (0.50) | ITKPIP5K1C | |
| Hydrochloric Acid SCHEMBL29207847 | 0.85 | ITK (0.49) | ITKPIP5K1C | |
| Hydrochloric Acid SCHEMBL29207792 | 0.85 | ITK (0.49) | ITKPIP5K1C | |
| SCHEMBL25190483 | 0.85 | ITK (0.49) | ITKPIP5K1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235715-A1 | COMPOUNDS FOR INHIBITING OR DEGRADING ITK, COMPOSITIONS, COMPRISING THE SAME METHODS OF THEIR MAKING AND METHODS OF THEIR USE | NURIX THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |