Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 7/20 | 0.60 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 4/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.44 |
| ▸ | CDK7 | P50613 | 1/20 | 0.44 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 2/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803696 | 0.94 | NAMPT (0.52) | NAMPTSCN9APDK4JAK1GRM5 | |
| SCHEMBL24669339 | 0.94 | NAMPT (0.52) | NAMPTSCN9APDK4JAK1GRM5 | |
| SCHEMBL29803278 | 0.91 | NAMPT (0.49) | NAMPTSCN9APDK4JAK1GRM5 | |
| SCHEMBL24670852 | 0.91 | NAMPT (0.49) | NAMPTSCN9APDK4JAK1GRM5 | |
| SCHEMBL29803406 | 0.90 | NAMPT (0.49) | NAMPTSCN9APDK4JAK1GRM5 | |
| SCHEMBL29803905 | 0.90 | NAMPT (0.49) | NAMPTSCN9APDK4JAK1GRM5 | |
| SCHEMBL24669383 | 0.90 | NAMPT (0.49) | NAMPTSCN9APDK4JAK1GRM5 | |
| SCHEMBL24670039 | 0.90 | NAMPT (0.49) | NAMPTSCN9APDK4JAK1GRM5 | |
| SCHEMBL24669437 | 0.90 | PDK4 (0.48) | NAMPTSCN9APDK4JAK1GRM5 | |
| SCHEMBL24670746 | 0.90 | NAMPT (0.61) | NAMPTSCN9APDK4JAK1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |