⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17675767 | 0.75 | — | — | |
| SCHEMBL2485301 | 0.74 | — | — | |
| SCHEMBL14701427 | 0.69 | — | — | |
| SCHEMBL14701428 | 0.69 | — | — | |
| SCHEMBL5836298 | 0.67 | — | — | |
| SCHEMBL5836301 | 0.67 | — | — | |
| SCHEMBL14701426 | 0.67 | — | — | |
| SCHEMBL2290274 | 0.63 | — | — | |
| SCHEMBL24663841 | 0.61 | — | — | |
| SCHEMBL23893253 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235715-A1 | COMPOUNDS FOR INHIBITING OR DEGRADING ITK, COMPOSITIONS, COMPRISING THE SAME METHODS OF THEIR MAKING AND METHODS OF THEIR USE | NURIX THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |