Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 3/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30007887 | 0.83 | NT5E (0.52) | NT5ELMNASMN1; SMN2ADORA2AADORA2B | |
| SCHEMBL27195103 | 0.83 | NT5E (0.52) | NT5ELMNASMN1; SMN2ADORA2AADORA2B | |
| SCHEMBL30008545 | 0.77 | NT5E (0.40) | NT5ELMNAADORA2AADORA2B | |
| SCHEMBL24672048 | 0.77 | NT5E (0.40) | NT5ELMNAADORA2AADORA2B | |
| SCHEMBL24672818 | 0.73 | NT5E (0.55) | NT5E | |
| SCHEMBL7666946 | 0.72 | PDE4D (0.60) | NT5EPNPLMNATP53HTT | |
| SCHEMBL7666938 | 0.72 | PDE4D (0.60) | NT5EPNPLMNATP53HTT | |
| SCHEMBL24672760 | 0.71 | NT5E (0.54) | NT5ELMNASMN1; SMN2ADORA2AADORA2B | |
| SCHEMBL30008458 | 0.71 | NT5E (0.54) | NT5ELMNASMN1; SMN2ADORA2AADORA2B | |
| SCHEMBL14303199 | 0.70 | DNMT1 (0.47) | NT5EPNPLMNATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237747-A1 | SMALL MOLECULAR CD73 ANTAGONIST AND USE THEREOF | 四川海思科制药有限公司 | 2022-11-17 | — | — | WO | disclosed |