Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL617486 | 0.82 | ATR (0.56) | ATR | |
| SCHEMBL2489811 | 0.75 | ATR (0.54) | ATR | |
| SCHEMBL20433675 | 0.74 | ATR (0.61) | ATR | |
| SCHEMBL10228653 | 0.73 | ATR (1.00) | ATR | |
| SCHEMBL2486688 | 0.73 | ATR (0.60) | ATR | |
| SCHEMBL19672783 | 0.73 | ATR (0.70) | ATR | |
| SCHEMBL10289491 | 0.73 | ATR (0.59) | ATR | |
| SCHEMBL615735 | 0.73 | ATR (0.53) | ATR | |
| SCHEMBL616191 | 0.73 | ATR (0.53) | ATR | |
| SCHEMBL10289660 | 0.73 | ATR (0.53) | ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370424-A1 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE | Vertex Pharmaceuticals Incorporated (US) | 2011-10-05 | — | — | EP | disclosed |