Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 9/20 | 0.56 |
| ▸ | TNF | P01375 | 10/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27206949 | 1.00 | NT5E (0.56) | NT5ETNFADORA2AADORA2B | |
| SCHEMBL30007983 | 1.00 | NT5E (0.56) | NT5ETNFADORA2AADORA2B | |
| SCHEMBL27206601 | 0.87 | NT5E (0.60) | NT5E | |
| SCHEMBL24672853 | 0.87 | NT5E (0.60) | NT5E | |
| SCHEMBL30008083 | 0.86 | NT5E (0.70) | NT5E | |
| SCHEMBL30008278 | 0.86 | NT5E (0.48) | NT5E | |
| SCHEMBL27206790 | 0.86 | NT5E (0.48) | NT5E | |
| SCHEMBL27195219 | 0.86 | NT5E (0.48) | NT5E | |
| SCHEMBL24672309 | 0.81 | NT5E (0.73) | NT5EADORA2AADORA2B | |
| SCHEMBL22104978 | 0.81 | NT5E (0.73) | NT5EADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4353732-A1 | SMALL MOLECULAR CD73 ANTAGONIST AND USE THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-04-17 | — | — | EP | disclosed |
| WO-2022237747-A1 | SMALL MOLECULAR CD73 ANTAGONIST AND USE THEREOF | 四川海思科制药有限公司 | 2022-11-17 | — | — | WO | disclosed |