Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23945757 | 1.00 | OPRL1 (0.35) | OPRL1 | |
| SCHEMBL23806860 | 0.99 | OPRL1 (0.36) | OPRL1 | |
| SCHEMBL23945431 | 0.99 | OPRL1 (0.36) | OPRL1 | |
| SCHEMBL25123533 | 0.99 | OPRL1 (0.36) | OPRL1 | |
| SCHEMBL23696272 | 0.98 | OPRL1 (0.34) | OPRL1 | |
| SCHEMBL25927756 | 0.97 | OPRL1 (0.35) | OPRL1 | |
| SCHEMBL25110978 | 0.95 | CHRM2 (0.34) | OPRL1 | |
| SCHEMBL25654354 | 0.95 | OPRL1 (0.34) | OPRL1 | |
| SCHEMBL23696518 | 0.90 | OPRL1 (0.36) | OPRL1 | |
| SCHEMBL25728719 | 0.90 | OPRL1 (0.36) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340570-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2022-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220340570-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | OPRL1 2347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.