Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 6/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24672032 | 0.79 | NT5E (0.52) | NT5E | |
| SCHEMBL24672837 | 0.66 | NT5E (0.59) | NT5E | |
| SCHEMBL24672508 | 0.66 | NT5E (0.61) | NT5E | |
| SCHEMBL24672678 | 0.64 | NT5E (0.32) | NT5E | |
| SCHEMBL24672836 | 0.62 | NT5E (0.45) | NT5E | |
| SCHEMBL24672838 | 0.61 | NT5E (0.47) | NT5E | |
| SCHEMBL24672024 | 0.58 | NT5E (0.56) | NT5ESCN1ASCN5ASCN8A | |
| SCHEMBL24672679 | 0.57 | NT5E (0.63) | NT5E | |
| SCHEMBL24672030 | 0.56 | NT5E (0.61) | NT5ESCN1ASCN5ASCN8A | |
| SCHEMBL22843456 | 0.55 | NT5E (0.71) | NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237747-A1 | SMALL MOLECULAR CD73 ANTAGONIST AND USE THEREOF | 四川海思科制药有限公司 | 2022-11-17 | — | — | WO | disclosed |