Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 18/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29613851 | 0.88 | NT5E (0.61) | NT5EADORA3ADORA2AADORA1 | |
| SCHEMBL22899487 | 0.88 | NT5E (0.61) | NT5EADORA3ADORA2AADORA1 | |
| SCHEMBL22899499 | 0.88 | NT5E (0.61) | NT5EADORA3ADORA2AADORA1 | |
| SCHEMBL24672832 | 0.86 | NT5E (0.48) | NT5E | |
| SCHEMBL22899620 | 0.84 | NT5E (0.56) | NT5EADORA3ADORA2AADORA1 | |
| SCHEMBL24672836 | 0.83 | NT5E (0.45) | NT5E | |
| SCHEMBL24672812 | 0.82 | NT5E (0.57) | NT5E | |
| SCHEMBL27206622 | 0.82 | NT5E (0.57) | NT5E | |
| SCHEMBL24672736 | 0.82 | NT5E (0.57) | NT5E | |
| SCHEMBL22899596 | 0.82 | NT5E (0.58) | NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4353732-A1 | SMALL MOLECULAR CD73 ANTAGONIST AND USE THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-04-17 | — | — | EP | disclosed |
| CN-117642411-A | Small molecule CD73 antagonists and uses thereof | 西藏海思科制药有限公司 | 2024-03-01 | — | — | CN | disclosed |
| WO-2022237747-A1 | SMALL MOLECULAR CD73 ANTAGONIST AND USE THEREOF | 四川海思科制药有限公司 | 2022-11-17 | — | — | WO | disclosed |
| WO-2022237747-A1 | SMALL MOLECULAR CD73 ANTAGONIST AND USE THEREOF | 四川海思科制药有限公司 | 2022-11-17 | — | — | WO | disclosed |