Methacrylic Acid

Methacrylic Acid

SCHEMBL246743

C=C(C)C(=O)O.C=C(C)C(=O)O.O=c1n(CCO)c(=O)n(CCO)c(=O)n1CCO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 2/20 0.34
PDE4A P27815 2/20 0.34
PDE4B Q07343 2/20 0.34
PDE4C Q08493 2/20 0.34
PDE4D Q08499 2/20 0.34
HSD17B10 Q99714 1/20 0.33
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
MEN1 O00255 2/20 0.30
KMT2A Q03164 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL248459 1.00 APEX1 (0.34) APEX1PDE4APDE4BPDE4CPDE4D
Methacrylic Acid SCHEMBL108959 1.00 APEX1 (0.34) APEX1PDE4APDE4BPDE4CPDE4D
Methacrylic Acid SCHEMBL2971459 0.87 APEX1 (0.53) APEX1PDE4APDE4BPDE4CPDE4D
Methacrylic Acid SCHEMBL2135482 0.87 APEX1 (0.53) APEX1PDE4APDE4BPDE4CPDE4D
Acetic Acid SCHEMBL30567453 0.87 APEX1 (0.39) APEX1PDE4APDE4BPDE4CPDE4D
Methacrylic Acid SCHEMBL10441412 0.83 APEX1 (0.32) APEX1
SCHEMBL9183999 0.82 APEX1 (0.33) APEX1PDE4APDE4BPDE4CPDE4D
Methacrylic Acid SCHEMBL3635510 0.80 APEX1 (0.37) APEX1ALDH1A1GAA
Methacrylic Acid SCHEMBL4450991 0.80 APEX1 (0.37) APEX1ALDH1A1GAA
Methacrylic Acid SCHEMBL1914676 0.80 APEX1 (0.37) APEX1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118302145-A Cosmetic water-in-oil emulsion comprising a specific water-soluble UV screening agent, a base, a volatile oil, a hydrophobic film-forming polymer, a polyoxyalkylene-alkylated linear polydimethylsiloxane and vitamin B3 莱雅公司 2024-07-05 CN disclosed
CN-117750937-A Cosmetic composition LVMH研究公司 2024-03-22 CN disclosed
CN-117042744-A Emulsion with neutralized water soluble masking agent, non-volatile non-phenylated silicone oil, film forming polymer and linear polyoxyalkylene alkylated polydimethyl siloxane emulsifier 莱雅公司 2023-11-10 CN disclosed
EP-4271352-A1 SKIN PERFECTING COMPOSITIONS AND METHODS OF USE L'OREAL (FR) 2023-11-08 EP disclosed
EP-4271358-A1 SKIN PERFECTING COSMETIC COMPOSITIONS AND METHODS OF USE L'OREAL (FR) 2023-11-08 EP disclosed
CN-116997315-A Cosmetic composition for improving skin and use method thereof 莱雅公司 2023-11-03 CN disclosed
CN-116887809-A Cosmetic composition for improving skin and use method thereof 莱雅公司 2023-10-13 CN disclosed
CN-111902127-B Composition for caring for and/or making up keratin materials 莱雅公司 2023-10-03 CN disclosed
CN-107921289-B Water-in-oil emulsion comprising microcapsules encapsulating an oily dispersion of at least one reflecting agent for caring for and/or making up keratin materials 莱雅公司 2023-09-22 CN disclosed
CN-116635001-A Composition for caring for and/or making up keratin materials 莱雅公司 2023-08-22 CN disclosed
US-7842755-B2 Dimethylvinylsilanol-endcapped polymethylphenylsiloxane, an organohydrogenpolysiloxane, a copolymer of a vinyl monomer and a vinyl monomer with hydrosilyl groups, platinum catalyst; two-stage thermal curing; high refractive index, light transmittance, adhesion, especially to thermoplastic resins DOW CORNING TORAY COMPANY, LTD. (JP) 2010-11-30 US disclosed
US-20080262158-A1 Dimethylvinylsilanol-endcapped polymethylphenylsiloxane, an organohydrogenpolysiloxane, a copolymer of a vinyl monomer and a vinyl monomer with hydrosilyl groups, platinum catalyst; two-stage thermal curing; high refractive index, light transmittance, adhesion, especially to thermoplastic resins DOW CORNING TORAY CO., LTD. (JP) 2008-10-23 US disclosed
EP-1781741-B1 CURABLE ORGANOPOLYSILOXANE COMPOSITION, METHOD OF CURING THEREOF, SEMICONDUCTOR DEVICE, AND ADHESION PROMOTER DOW CORNING TORAY CO LTD (JP) 2008-08-27 EP disclosed
EP-1781741-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITION, METHOD OF CURING THEREOF, SEMICONDUCTOR DEVICE, AND ADHESION PROMOTER Dow Corning Toray Co., Ltd. (JP) 2007-05-09 EP disclosed
WO-2006058793-A1 COSMETIC COMPOSITION COMPRISING A VINYL POLYMER CONTAINING AT LEAST ONE CARBOSILOXANE DENDRIMER-BASED UNIT L'ORÉAL (FR) 2006-06-08 WO disclosed
WO-2006058795-A1 TWO-COAT COSMETIC PRODUCT, USES THEREOF AND MAKEUP KIT CONTAINING THIS PRODUCT L'OREAL (FR) 2006-06-08 WO disclosed
WO-2006011676-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITION, METHOD OF CURING THEREOF, SEMICONDUCTOR DEVICE, AND ADHESION PROMOTER DOW CORNING TORAY CO., LTD. (JP) 2006-02-02 WO disclosed
EP-0963751-B1 Cosmetic raw material, cosmetic product, and method for manufacturing cosmetic raw material DOW CORNING TORAY SILICONE (JP) 2004-09-01 EP disclosed
US-6280748-B1 TREATING SKIN OR HAIR BY APPLYING TO SKIN OR HAIR COSMETIC PRODUCT COMPRISING SOLUTION OR DISPERSION OF POLYMER IN LIQUID SELECTED FROM SILICONE OILS, ORGANIC OILS, ALCOHOLS AND WATER, POLYMER HAVING CARBOSILOXANE DENDRIMER IN ITS SIDE CHAIN DOW CORNING TORAY SILICONE, LTD. (JP) 2001-08-28 US disclosed
EP-0963751-A2 Cosmetic raw material, cosmetic product, and method for manufacturing cosmetic raw material Dow Corning Toray Silicone Company, Ltd. (JP) 1999-12-15 EP disclosed