Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 16/20 | 0.53 |
| ▸ | HTR2A | P28223 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 4/20 | 0.41 |
| ▸ | CBLB | Q13191 | 1/20 | 0.41 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24675535 | 1.00 | HTR2C (0.53) | HTR2CHTR2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL24674699 | 1.00 | HTR2C (0.53) | HTR2CHTR2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL31245455 | 0.88 | HTR2C (0.43) | HTR2CHTR2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL24675334 | 0.85 | HTR2C (0.56) | HTR2CHTR2AALDH1A1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL30658102 | 0.84 | HTR2C (0.55) | HTR2CHTR2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL31245115 | 0.82 | KMT2A (0.63) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL30729642 | 0.81 | HTR2C (0.45) | HTR2CHTR2ACYP3A4HTR2B | |
| SCHEMBL24674980 | 0.81 | HTR2C (0.50) | HTR2CHTR2AHTR2B | |
| SCHEMBL26915100 | 0.81 | HTR2C (0.45) | HTR2CHTR2ACYP3A4HTR2B | |
| SCHEMBL31245229 | 0.81 | HTR2C (0.48) | HTR2CHTR2ACYP3A4HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289845-A1 | TRIHETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Shanghai Apeiron Therapeutics Company Limited (CN) | 2023-12-13 | — | — | EP | disclosed |
| EP-4289845-A1 | TRIHETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Shanghai Apeiron Therapeutics Company Limited (CN) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022223022-A1 | FUSED-RING HETEROCYCLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2022-10-27 | — | — | WO | disclosed |