Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.37 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12635273 | 0.89 | BCHE (0.41) | HRH2HRH1POLBHTTSMN1; SMN2 | |
| SCHEMBL12635280 | 0.89 | BCHE (0.41) | HRH2HRH1POLBHTTSMN1; SMN2 | |
| SCHEMBL12635261 | 0.89 | POLB (0.47) | HRH2HRH1POLBHTTSMN1; SMN2 | |
| SCHEMBL5744835 | 0.82 | HRH2 (0.44) | HRH2HRH1POLBHTTSMN1; SMN2 | |
| SCHEMBL12226501 | 0.81 | HRH2 (0.44) | HRH2HRH1POLBHTTSMN1; SMN2 | |
| SCHEMBL5744837 | 0.81 | HRH2 (0.44) | HRH2HRH1POLBHTTSMN1; SMN2 | |
| SCHEMBL12226499 | 0.81 | HRH2 (0.44) | HRH2HRH1POLBHTTSMN1; SMN2 | |
| SCHEMBL13993975 | 0.79 | PDCD1 (0.46) | POLBHTTSMN1; SMN2PAOXLTA4H | |
| SCHEMBL14520291 | 0.79 | PDCD1 (0.46) | POLBHTTSMN1; SMN2PAOXLTA4H | |
| SCHEMBL14197721 | 0.79 | POLB (0.50) | POLBHTTSMN1; SMN2PAOXALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022223022-A1 | FUSED-RING HETEROCYCLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2022-10-27 | — | — | WO | disclosed |