Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.72 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.72 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | USP2 | O75604 | 2/20 | 0.67 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.67 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.67 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.66 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.66 |
| ▸ | CASP7 | P55210 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | BLM | P54132 | 2/20 | 0.65 |
| ▸ | MDM4 | O15151 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL246889 | 0.96 | GPBAR1 (0.71) | GPBAR1NR1H4CYP3A4PDE3ALMNA | |
| SCHEMBL2369521 | 0.96 | GPBAR1 (0.71) | GPBAR1NR1H4CYP3A4PDE3ALMNA | |
| SCHEMBL7546767 | 0.96 | GPBAR1 (0.71) | GPBAR1NR1H4CYP3A4PDE3ALMNA | |
| SCHEMBL2637801 | 0.96 | GPBAR1 (0.75) | GPBAR1NR1H4CYP3A4PDE3ALMNA | |
| SCHEMBL25791236 | 0.96 | GPBAR1 (0.75) | GPBAR1NR1H4CYP3A4PDE3ALMNA | |
| SCHEMBL25791216 | 0.96 | GPBAR1 (0.75) | GPBAR1NR1H4CYP3A4PDE3ALMNA | |
| SCHEMBL1287858 | 0.95 | GPBAR1 (0.78) | GPBAR1NR1H4CYP3A4PDE3ALMNA | |
| SCHEMBL1758946 | 0.94 | GPBAR1 (0.67) | GPBAR1NR1H4CYP3A4PDE3ALMNA | |
| SCHEMBL8646650 | 0.94 | GPBAR1 (0.66) | GPBAR1NR1H4CYP3A4PDE3ALMNA | |
| SCHEMBL2638871 | 0.93 | GPBAR1 (0.74) | GPBAR1NR1H4CYP3A4LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367839-A2 | METHODS AND COMPOSITIONS FOR INHIBITING CLOSTRIDIUM DIFFICILE SPORE GERMINATION AND OUTGROWTH | Tufts University (US) | 2011-09-28 | — | — | EP | disclosed |
| WO-2010062369-A2 | METHODS AND COMPOSITIONS FOR INHIBITING CLOSTRIDIUM DIFFICILE SPORE GERMINATION AND OUTGROWTH | TUFTS UNIVERSITY (US) | 2010-06-03 | — | — | WO | disclosed |