Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 8/20 | 0.57 |
| ▸ | RBP4 | P02753 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2470666 | 0.91 | SCD (0.51) | SCDDCTPP1 | |
| SCHEMBL2467249 | 0.90 | SCD (0.60) | SCDDCTPP1 | |
| SCHEMBL2464871 | 0.90 | SCD (0.60) | SCDDCTPP1 | |
| SCHEMBL2471428 | 0.90 | SCD (0.55) | SCDDCTPP1 | |
| SCHEMBL2466621 | 0.89 | SCD (0.58) | SCDDCTPP1 | |
| SCHEMBL938240 | 0.88 | SCD (0.71) | SCDRBP4DCTPP1 | |
| SCHEMBL2471098 | 0.86 | SCD (0.53) | SCDDCTPP1 | |
| SCHEMBL2476294 | 0.85 | SCD (0.59) | SCDDCTPP1 | |
| SCHEMBL2474516 | 0.85 | SCD (0.74) | SCDDCTPP1 | |
| SCHEMBL2465310 | 0.85 | SCD (0.60) | SCDDCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648874-B1 | PIPERAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2011-10-05 | — | — | EP | claimed |
| EP-1846035-B1 | COMBINATION THERAPY | XENON PHARMACEUTICALS INC (CA) | 2011-09-21 | — | — | EP | claimed |