Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 20/20 | 0.49 |
| ▸ | CDK2 | P24941 | 20/20 | 0.49 |
| ▸ | CDK1 | P06493 | 5/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.49 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.49 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.49 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.49 |
| ▸ | CCND1 | P24385 | 14/20 | 0.45 |
| ▸ | CDK6 | Q00534 | 14/20 | 0.45 |
| ▸ | CDK4 | P11802 | 4/20 | 0.44 |
| ▸ | CCND3 | P30281 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24676442 | 0.94 | CDK2 (0.53) | CCNE1CDK2CDK1CCNB1CCNB2 | |
| SCHEMBL24676449 | 0.90 | CDK2 (0.49) | CCNE1CDK2CDK1CCNB1CCNB2 | |
| SCHEMBL24675945 | 0.88 | CDK2 (0.51) | CCNE1CDK2CDK1CCNB1CCNB2 | |
| SCHEMBL24676672 | 0.88 | CDK2 (0.51) | CCNE1CDK2CDK1CCNB1CCNB2 | |
| SCHEMBL24676670 | 0.87 | CDK2 (0.49) | CCNE1CDK2CDK1CCNB1CCNB2 | |
| SCHEMBL24676680 | 0.87 | CDK2 (0.49) | CCNE1CDK2CDK1CCNB1CCNB2 | |
| SCHEMBL24676683 | 0.87 | CDK2 (0.49) | CCNE1CDK2CDK1CCNB1CCNB2 | |
| SCHEMBL24676489 | 0.86 | CDK2 (0.55) | CCNE1CDK2CDK1CCNB1CCNB2 | |
| SCHEMBL24676584 | 0.86 | CDK2 (0.53) | CCNE1CDK2CDK1CCNB1CCNB2 | |
| SCHEMBL24676575 | 0.86 | CDK2 (0.53) | CCNE1CDK2CDK1CCNB1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155941-A1 | CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-07-28 | — | — | WO | disclosed |