SCHEMBL24676557

SCHEMBL24676557

c1ccc2c(c1)oc1c2ccc2c3ccccc3n(-c3ccc(-c4ccc(-c5ccc(-n6c7ccccc7c7ccc8c9ccccc9oc8c76)cc5)cc4)cc3)c21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALOX5 P09917 2/20 0.38
ALDH1A1 P00352 5/20 0.36
HTT P42858 1/20 0.36
PPARG P37231 4/20 0.35
RXFP1 Q9HBX9 4/20 0.35
NR2E3 Q9Y5X4 4/20 0.35
NCOR2 Q9Y618 4/20 0.35
NPSR1 Q6W5P4 2/20 0.35
HDAC4 P56524 1/20 0.35
KMT2A Q03164 3/20 0.33
LMNA P02545 2/20 0.33
AHR P35869 2/20 0.33
POLB P06746 2/20 0.33
PLA2G2A P14555 1/20 0.33
PLA2G4A P47712 1/20 0.33
PRKDC P78527 1/20 0.33
PGR P06401 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9889953 1.00 KDM4E (0.41) KDM4EATML3MBTL1ALOX5ALDH1A1
SCHEMBL22710438 0.99 KDM4E (0.43) KDM4EATML3MBTL1ALOX5ALDH1A1
SCHEMBL24676560 0.99 KDM4E (0.43) KDM4EATML3MBTL1ALOX5ALDH1A1
SCHEMBL17246035 0.97 KDM4E (0.42) KDM4EATML3MBTL1ALOX5ALDH1A1
SCHEMBL9889955 0.95 KDM4E (0.44) KDM4EATML3MBTL1ALOX5ALDH1A1
SCHEMBL17246074 0.94 KDM4E (0.47) KDM4EATML3MBTL1ALOX5ALDH1A1
SCHEMBL24700566 0.93 AHR (0.41) KDM4EATML3MBTL1ALOX5ALDH1A1
SCHEMBL24174741 0.93 AHR (0.38) KDM4EATML3MBTL1ALOX5ALDH1A1
SCHEMBL15583042 0.93 AHR (0.38) KDM4EATML3MBTL1ALOX5ALDH1A1
SCHEMBL17246059 0.93 KDM4E (0.39) KDM4EATML3MBTL1ALOX5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220238815-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND, AND ELECTRONIC APPLIANCE IDEMITSU KOSAN CO.,LTD. (JP) 2022-07-28 US disclosed