SCHEMBL24677705

SCHEMBL24677705

Cc1cc(O)cc(C(=O)F)c1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.41
ACHE P22303 2/20 0.41
ALOX15 P16050 2/20 0.39
CHRM1 P11229 1/20 0.39
MAOA P21397 1/20 0.39
TBXA2R P21731 1/20 0.39
ADRA1A P35348 1/20 0.39
HTR2B P41595 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 2/20 0.33
HCAR1 Q9BXC0 1/20 0.33
CA5A P35218 1/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
HSP90AA1 P07900 1/20 0.32
ATM Q13315 1/20 0.32
HPGD P15428 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL89590 0.80 CYP3A4 (0.52) CYP3A4ACHEALOX15CHRM1MAOA
SCHEMBL2318334 0.75 CYP3A4 (0.56) CYP3A4ACHEALOX15SMN1; SMN2TDP1
SCHEMBL253926 0.72 CYP3A4 (0.58) CYP3A4ACHEALOX15CHRM1MAOA
Acetic Acid SCHEMBL6559794 0.72 CYP3A4 (0.52) CYP3A4ACHEALOX15CHRM1MAOA
Methane SCHEMBL27301821 0.70 CYP3A4 (0.55) CYP3A4ACHEALOX15CHRM1MAOA
SCHEMBL11641080 0.70 HDAC1 (0.34) SMN1; SMN2TDP1MEN1KMT2A
SCHEMBL18311221 0.68 CYP3A4 (0.48) CYP3A4ACHEALOX15CHRM1MAOA
SCHEMBL166744 0.68 CYP3A4 (0.48) CYP3A4ACHEALOX15CHRM1MAOA
SCHEMBL30888533 0.68 CYP3A4 (0.48) CYP3A4ACHEALOX15CHRM1MAOA
SCHEMBL12396449 0.67 CYP3A4 (0.46) CYP3A4ACHEALOX15CHRM1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022177078-A1 ANTIBACTERIAL AGENT COMPRISING TRIFLUOROMETHYLATED HYDROQUINONE 중앙대학교 산학협력단 2022-08-25 WO disclosed