⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16084762 | 0.71 | PHGDH (0.31) | — | |
| SCHEMBL12980709 | 0.69 | — | — | |
| SCHEMBL190413 | 0.69 | — | — | |
| SCHEMBL24677726 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL1927289 | 0.67 | POLB (0.41) | — | |
| SCHEMBL16079972 | 0.67 | — | — | |
| SCHEMBL24677734 | 0.67 | — | — | |
| SCHEMBL359361 | 0.66 | — | — | |
| SCHEMBL81623 | 0.66 | — | — | |
| SCHEMBL172577 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116934-A1 | KRASG12D PROTEIN HYDROLYSIS REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州泽璟生物制药股份有限公司 | 2023-06-29 | — | — | WO | disclosed |
| WO-2022188819-A1 | SOS1 PROTEOLYSIS MODULATOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 苏州泽璟生物制药股份有限公司 | 2022-09-15 | — | — | WO | disclosed |