Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 2/20 | 0.48 |
| ▸ | PRKCI | P41743 | 2/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.41 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 12/20 | 0.37 |
| ▸ | JAK3 | P52333 | 12/20 | 0.37 |
| ▸ | JAK2 | O60674 | 12/20 | 0.37 |
| ▸ | TYK2 | P29597 | 6/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30084241 | 1.00 | AXL (0.48) | AXLPRKCIRIPK1TTBK1TTBK2 | |
| SCHEMBL30084219 | 0.86 | AXL (0.48) | AXLPRKCITTBK1TTBK2CSNK1D | |
| SCHEMBL30084243 | 0.86 | AXL (0.48) | AXLPRKCITTBK1TTBK2AAK1 | |
| SCHEMBL30084193 | 0.86 | AXL (0.55) | AXLPRKCITTBK1TTBK2CSNK1D | |
| SCHEMBL24678675 | 0.86 | AXL (0.48) | AXLPRKCITTBK1TTBK2CSNK1D | |
| SCHEMBL24678652 | 0.86 | AXL (0.48) | AXLPRKCITTBK1TTBK2AAK1 | |
| SCHEMBL24678393 | 0.86 | AXL (0.55) | AXLPRKCITTBK1TTBK2CSNK1D | |
| SCHEMBL24678406 | 0.86 | AXL (0.48) | AXLPRKCIRIPK1TTBK1TTBK2 | |
| SCHEMBL30084216 | 0.86 | AXL (0.48) | AXLPRKCIRIPK1TTBK1TTBK2 | |
| SCHEMBL24678401 | 0.86 | AXL (0.50) | AXLPRKCITTBK1TTBK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022247676-A1 | COMPOUND WITH DIPYRROLOPYRIDINE STRUCTURE, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 南京康屹生物医药中心(有限合伙) | 2022-12-01 | — | — | WO | disclosed |
| CN-115385911-A | Compound with dipyrrolopyridine structure, preparation method and medical application | 南京康屹生物医药中心(有限合伙) | 2022-11-25 | — | — | CN | disclosed |
| CN-113292561-A | Compound with dipyrrolopyridine structure, preparation method and medical application | 中国药科大学 | 2021-08-24 | — | — | CN | disclosed |