Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 2/20 | 0.43 |
| ▸ | PRKCI | P41743 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.39 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.38 |
| ▸ | KIT | P10721 | 2/20 | 0.38 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30084267 | 1.00 | AXL (0.43) | AXLPRKCIPIK3CAMTORPDK1 | |
| SCHEMBL30084238 | 0.85 | AXL (0.43) | AXLPRKCITTBK1TTBK2AAK1 | |
| SCHEMBL30084183 | 0.85 | AXL (0.50) | AXLPRKCITTBK1TTBK2AAK1 | |
| SCHEMBL24678679 | 0.85 | AXL (0.43) | AXLPRKCITTBK1TTBK2AAK1 | |
| SCHEMBL24678169 | 0.85 | AXL (0.50) | AXLPRKCITTBK1TTBK2AAK1 | |
| SCHEMBL24678652 | 0.84 | AXL (0.48) | AXLPRKCIPIK3CAMTORPDK1 | |
| SCHEMBL30084243 | 0.84 | AXL (0.48) | AXLPRKCIPIK3CAMTORPDK1 | |
| SCHEMBL24678401 | 0.84 | AXL (0.50) | AXLPRKCITTBK1TTBK2AAK1 | |
| SCHEMBL30084261 | 0.84 | AXL (0.50) | AXLPRKCITTBK1TTBK2AAK1 | |
| SCHEMBL24678141 | 0.82 | PTGDR2 (0.42) | AXLPRKCITTBK1AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022247676-A1 | COMPOUND WITH DIPYRROLOPYRIDINE STRUCTURE, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 南京康屹生物医药中心(有限合伙) | 2022-12-01 | — | — | WO | disclosed |